Clomiphene is primarily administered for which condition?

Clomiphene is primarily used to treat infertility, particularly in women who are experiencing ovulatory dysfunction. It is a selective estrogen receptor modulator (SERM) that works by blocking estrogen receptors in the hypothalamus. This inhibition leads to an increase in the release of gonadotropin-releasing hormone (GnRH), which in turn stimulates the pituitary gland to secrete more follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Increased levels of these hormones promote the maturation of ovarian follicles and can induce ovulation, making clomiphene a valuable therapeutic option for women trying to conceive.

While clomiphene may have some secondary effects on various reproductive conditions, its primary and most recognized use is in the management of infertility in women who are not ovulating regularly.