Peroxisomes are involved in which of the following conditions?

Peroxisomes are organelles that play a crucial role in various metabolic processes, including the breakdown of fatty acids and the detoxification of hydrogen peroxide. Zellweger syndrome is a genetic disorder caused by a deficiency of peroxisomal enzymes, leading to the accumulation of very long-chain fatty acids and other metabolites in the body due to impaired peroxisomal function.

This condition is characterized by a range of symptoms including developmental delays, seizures, and liver dysfunction, all stemming from the inability of the cells to perform essential metabolic functions that peroxisomes normally facilitate. The correlation between Zellweger syndrome and peroxisome dysfunction is well established, making it the condition associated with involvement of peroxisomes.

In contrast, the other conditions listed do not have a direct link to peroxisomal function. Marfan syndrome is a connective tissue disorder resulting from mutations in the fibrillin gene. Becker muscular dystrophy is a genetic disorder caused by mutations in the dystrophin gene leading to muscle degeneration. Cystic fibrosis, a genetic disorder affecting the respiratory and digestive systems, is caused by mutations in the CFTR gene and is unrelated to peroxisomal activity. Hence, Zellweger syndrome stands out as the correct