Which type of sex cord tumor is associated with estrogen production?

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The granulosa cell tumor is the type of sex cord tumor that is associated with estrogen production. This tumor originates from the granulosa cells of the ovarian follicles, which are responsible for the production of estrogen. Granulosa cell tumors are known for their ability to synthesize and secrete estrogen, leading to conditions like endometrial hyperplasia or even endometrial carcinoma due to prolonged exposure to elevated estrogen levels.

In contrast, yolk sac tumors primarily produce alpha-fetoprotein rather than hormones like estrogen. Sertoli-leydig tumors can produce androgens, which may lead to virilization rather than estrogenic effects. Dysgerminoma is a germ cell tumor that primarily produces human chorionic gonadotropin (hCG) and does not typically produce estrogen. Thus, granulosa cell tumors stand out for their estrogenic activity among the various types of sex cord tumors.

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